Autoimmune response following influenza H1N1 vaccination in patients with juvenile idiopathic arthritis

نویسندگان

  • Nadia E Aikawa
  • Claudia Goldenstein-Schainberg
  • M Vendramini
  • Lucia MA Campos
  • Carla G Saad
  • Julio B Moraes
  • Alberto Duarte
  • Alex R Precioso
  • Maria CST Timenetsky
  • E Bonfá
  • Clovis A Silva
چکیده

Methods 58 JIA patients were vaccinated with cepa A/California/ 7/2009 (NYMC X-179A) anti-H1N1. All participants received 1 dose of immunization, those <9yrs of age received a second dose 3weeks apart. All sera were evaluated before and 3weeks after complete vaccination. Serology against H1N1 virus was performed by hemagglutination inhibition antibody assay, antinuclear antibodies (ANA) by IIF, IgM and IgG anticardiolipin (aCL) by ELISA, and rheumatoid factor (RF) by latex fixation test.

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عنوان ژورنال:

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2011